Yes. Our formulations specifically address sensitive skin concerns and underwent Repeated-Insult Patch Testing (RIPT) on sensitive skin participants, confirming their safety and non-irritating properties. Unlike many post-procedure products, these contain no fragrance mix, parabens, formaldehyde-releasing preservatives, or sodium lauryl sulfate, common sensitizers that can complicate recovery. The TRPV1-targeting approach actually reduces sensitivity by modulating inflammatory pathways, making these formulations particularly beneficial for rosacea patients undergoing microneedling treatments.

While no topical product eliminates the biological healing timeline required after creating thousands of microchannels in your skin, clinical trials demonstrated measurable improvements in inflammation markers and texture recovery. Participants experienced a 21% reduction in erythema and 63% improvement in skin texture within four weeks. This translates to visibly reduced redness and faster return to normal appearance after SkinPen, Dermapen, Vivace, or Rejuvapen sessions, though complete dermal remodeling still requires the expected 4-6 week timeframe.

After complete re-epithelialization of microchannels, typically 24-48 hours for professional treatments like SkinPen and Dermapen, 12-24 hours for at-home BeautyBio GloPRO, you may gradually reintroduce makeup. Choose mineral-based, non-comedogenic formulations without fragrance or irritating preservatives. Apply The Purifier for cleansing, follow with The Catalyst and The Day Formula, allowing 2 minutes for complete absorption before makeup application. Avoid makeup during the initial healing phase when microchannels remain open and vulnerable to contamination.

Post-microneedling skin requires extended recovery before tolerating active ingredients. For professional treatments with SkinPen, Dermapen, Vivace, or Rejuvapen, wait minimum 5-7 days before reintroducing retinoids or exfoliating acids. For at-home BeautyBio GloPRO or similar devices, wait 3-5 days. Begin with the lowest concentration every third night, gradually increasing frequency as tolerance develops. Premature reintroduction risks hyperpigmentation and compromised collagen remodeling. We recommend continuing Dr Rossi formulations as your primary regimen to extend results and prevent inflammatory conditions.

Traditional anti-inflammatories like corticosteroids broadly suppress immune responses, potentially interfering with the controlled inflammation necessary for collagen synthesis following microneedling. The sea anemone biomimetic peptide in our formulations specifically antagonizes TRPV1 receptors. the precise trigger point for microneedling-induced inflammation, without suppressing beneficial healing activity. Research published in peer-reviewed dermatology journals demonstrates this targeted approach reduces inflammatory mediators while supporting optimal collagen production and barrier restoration.

Continue your post-microneedling care protocol between SkinPen, Dermapen, Vivace, Rejuvapen, or BeautyBio GloPRO sessions. Maintaining skin barrier integrity and managing baseline inflammation between treatments optimizes outcomes for subsequent sessions. Use The Purifier for gentle cleansing, The Catalyst for ongoing TRPV1 modulation, and The Day Formula for protection and hydration throughout your treatment series. This approach ensures your skin enters each session in optimal condition, potentially allowing for more aggressive treatment parameters and better cumulative results.

Dr Rossi formulations address sensitive and sensitized skin beyond post-procedure recovery. While particularly beneficial following SkinPen, Dermapen, Vivace, Rejuvapen, or BeautyBio GloPRO treatments, continued use helps modulate inflammatory responses to environmental stressors, addressing conditions like rosacea, premature aging, hyperpigmentation, and chronic sensitivity. The gentle, non-irritating formulations demonstrated excellent safety profiles in clinical testing for continuous use. Many patients continue these products indefinitely as their primary skincare regimen.

While these products demonstrated excellent safety profiles in clinical testing, individual responses vary. Contact your treating practitioner or dermatologist immediately if you develop increasing pain, purulent drainage, severe edema, expanding erythema, or fever; these may indicate infection requiring medical intervention unrelated to topical products. For concerns about product tolerance, discontinue use and consult your physician. Normal post-microneedling experiences include mild stinging upon application, temporary redness increase, and slight warmth. These typically resolve within 10-15 minutes and diminish with continued use.

While The Catalyst alone provides significant TRPV1 antagonism and anti-inflammatory benefits following microneedling, the three-product protocol addresses different aspects of optimal recovery. The Purifier ensures gentle cleansing without barrier disruption, The Catalyst targets inflammation at its cellular source, and The Day Formula provides hydration and SPF protection essential for post-procedure healing. Clinical trial participants used complete protocols, achieving the published results. For budget considerations, prioritize The Catalyst as the foundational product, adding The Purifier and Day Formula for comprehensive support.

Erythema duration varies by treatment depth and individual healing capacity. Professional treatments with SkinPen, Dermapen, Vivace, or Rejuvapen typically produce 24-72 hours of pronounced redness, with residual pink tone persisting 5-7 days. RF microneedling (Vivace) may create slightly longer erythema due to combined thermal injury. At-home BeautyBio GloPRO treatments produce 12-24 hours of mild erythema. Clinical data demonstrates that TRPV1 antagonism reduces erythema intensity by 21% and may shorten visible redness duration by modulating the inflammatory cascade at its cellular origin. Persistent redness beyond expected timeframes warrants dermatologist evaluation.

Physical activity restrictions depend on treatment intensity and sweat's impact on healing microchannels. After professional microneedling procedures, avoid exercise for 24-48 hours as elevated heart rate increases facial blood flow and prolongs erythema, while sweat introduces bacteria and irritants to open microchannels. For at-home BeautyBio GloPRO sessions, limit intense exercise for 12-24 hours but gentle walking remains acceptable. Once you resume activity, cleanse immediately post-exercise using The Purifier with lukewarm water, then reapply The Catalyst and barrier protection. Elevated core temperature can trigger TRPV1 activation, potentially increasing inflammation during the critical healing window.

Mild peeling represents normal epithelial turnover following microneedling, particularly after professional treatments with deeper needle penetration like SkinPen or Dermapen. Resist the urge to pick, pull, or manually remove loosening skin. Forced removal creates irregular texture, prolongs healing, and increases infection and scarring risk. Peeling typically begins days 3-5 and continues through day 7-10. Apply The Catalyst followed by The Day Formula to softened, dampened skin, gently patting rather than rubbing. The peptide complex supports organized desquamation while maintaining barrier integrity beneath peeling layers.

Cleansing protocols differ by treatment type. After professional treatments like SkinPen, Dermapen, Vivace, or Rejuvapen, wait 12-24 hours before gentle cleansing to allow initial microchannel closure. Use The Purifier with lukewarm water—avoid hot water (activates TRPV1 receptors, increasing inflammation), mechanical cleansing devices, washcloths, or scrubbing motions for minimum 5-7 days. For at-home BeautyBio GloPRO treatments, resume gentle cleansing after 6-12 hours. Pat skin dry rather than rubbing. Apply The Catalyst to slightly damp skin for enhanced absorption and barrier support during this vulnerable phase.

Tightness and mild discomfort represent common post-microneedling experiences resulting from controlled injury, barrier disruption, and altered nerve signaling. Professional treatments create more pronounced tightness that may persist 3-5 days as microchannels heal. The TRPV1 receptor mediates much of this sensory experience; published research demonstrates that TRPV1 antagonists reduce subjective discomfort scores in post-procedure patients. Apply The Catalyst liberally during this phase, as the biomimetic peptide specifically addresses the receptor pathway transmitting these uncomfortable sensations. However, progressively worsening pain or burning that interferes with daily activities requires physician evaluation to exclude complications.

Cold therapy provides benefits for post-microneedling inflammation management when applied correctly. During the first 24 hours after professional treatments, gentle cooling reduces edema and provides comfort. Use clean, soft cloths dampened with cool (not ice-cold) water, applied for 10-15 minutes every 2-3 hours. Avoid direct ice application as extreme cold can damage healing tissue. Never apply cold compresses over topical products; instead, cool first, pat dry gently, then apply The Catalyst. Cold temperatures may enhance TRPV1-targeting peptide effectiveness by reducing baseline receptor activity. Discontinue if you experience increased pain or blanching persisting beyond compress removal.

Results timeline varies by treatment goals and intensity. Initial improvements in skin texture and radiance appear within 1-2 weeks following professional SkinPen, Dermapen, Vivace, or Rejuvapen treatments as inflammation subsides and cellular turnover accelerates. Deeper benefits, collagen remodeling, scar improvement, pore refinement, emerge over 4-6 weeks as new collagen matures. Optimal results typically manifest 8-12 weeks post-treatment. Multiple treatment sessions spaced 4-6 weeks apart produce cumulative improvements. At-home BeautyBio GloPRO treatments require consistent use over 8-12 weeks for visible benefits due to more superficial needle penetration.

Yes, our formulations are ophthalmologist-tested and safe for periorbital application following microneedling treatments around the delicate eye area. Clinical trials included periorbital applications, demonstrating significant improvements in fine lines and texture. Apply products carefully to avoid direct eye contact. When treating the full face including periorbital regions after comprehensive microneedling, use gentle dabbing motions with your ring finger rather than rubbing to avoid mechanical irritation of delicate tissue during the healing phase.

Professional treatments with SkinPen, Dermapen, Vivace, or Rejuvapen use longer needles (0.5-2.5mm) that penetrate deeper into the dermis, creating more significant collagen remodeling for concerns like acne scarring, deep wrinkles, and skin laxity. These require longer recovery periods but produce more dramatic results. At-home devices like BeautyBio GloPRO use shorter needles (0.25-0.5mm) that remain in the epidermis, offering gentler improvement in texture, tone, and product absorption with minimal downtime. Both modalities benefit from TRPV1-targeting post-care protocols, though professional treatments require more intensive barrier support.