Yes. Our formulations specifically address sensitive skin concerns and underwent Repeated-Insult Patch Testing (RIPT) on sensitive skin participants. Unlike many post-peel products, these contain no fragrance mix, parabens, formaldehyde-releasing preservatives, or sodium lauryl sulfate - common sensitizers that complicate recovery from glycolic acid peels, TCA peels, and other treatments. The TRPV1-targeting approach actually reduces sensitivity by modulating inflammatory pathways that cause burning, stinging, and prolonged redness. However, if you have known allergies to specific ingredients, review the complete ingredient list with your dermatologist before use.

While no topical product eliminates the biological healing timeline required after chemical exfoliation, clinical trials demonstrated measurable improvements in inflammation markers and texture recovery. Our. clinical trial participants experienced a 21% reduction in erythema (redness) and 63% improvement in skin texture within four weeks. This translates to visibly reduced redness and improvement in the visible signs of aging.

After complete re-epithelialization occurs, typically 2-4 days for light glycolic acid peels, 5-7 days for Jessner's peel, 7-10 days for TCA peels, you may gradually reintroduce makeup. Choose mineral-based, non-comedogenic formulations without fragrance or irritating preservatives. Apply The Catalyst and The Day Formula first, allowing 15-20 minutes for complete absorption before makeup application. Avoid makeup during initial healing when skin barrier is compromised, particularly after medium-depth or deep chemical peels.

We recommend continuing with Dr Rossi as your primary skincare regimen to maintain results and prevent inflammatory conditions. When considering other products not specifically formulated for sensitive skin, know that post-peel skin requires extended recovery before tolerating additional active ingredients. For medium-depth peels like Jessner's peel or TCA peels, wait minimum 6-8 weeks before reintroducing retinoids or exfoliating acids. For light glycolic acid peels or salicylic acid peels, wait 3-4 weeks. Begin with the lowest concentration every third night, gradually increasing frequency as tolerance develops. Premature reintroduction risks hyperpigmentation and compromised collagen remodeling. Your dermatologist should evaluate healing progress before approving active ingredient

Traditional soothing ingredients like aloe or chamomile provide surface-level comfort but don't address the underlying inflammatory cascade triggered by chemical peels. The sea anemone biomimetic peptide in our formulations specifically antagonizes TRPV1 receptors, the precise cellular trigger for peel-induced inflammation, burning sensations, and redness, without suppressing beneficial immune activity required for tissue repair. Research published in peer-reviewed dermatology journals demonstrates this targeted approach reduces inflammatory mediators while supporting optimal collagen synthesis and barrier restoration following glycolic acid peels, TCA peels, Jessner's peel, and other chemical exfoliation treatments.I'm planning a series of chemical peels.

We recommend maintaining your post-peel care protocol between successive glycolic acid peels, salicylic acid peels, or other treatments. Sustaining skin barrier integrity and managing baseline inflammation between sessions optimizes outcomes for subsequent peels. Continue using The Purifier, The Catalyst, and The Day Formula throughout your treatment series, discontinuing only 48 hours before your next peel per your provider's protocol. This approach ensures your skin enters each treatment in optimal condition, potentially allowing for more effective results and better cumulative benefits across your peel series.

Dr Rossi is formulated for sensitive and sensitized skin, making it ideal for both post-procedure recovery and daily maintenance. While particularly beneficial following glycolic acid peels, TCA peels, Jessner's peel, and other treatments, we recommend these products as part of your ongoing routine. Long-term use helps modulate inflammatory responses to environmental stressors, addressing conditions like rosacea, premature aging, hyperpigmentation, reactive skin, and sensitivity. The gentle, non-irritating formulations suit daily use indefinitely. Clinical trials evaluated continuous four-week use, but extended use appears safe based on ingredient profiles and mechanism of action.

While these products demonstrated excellent safety profiles in clinical testing, individual responses vary. Contact your treating dermatologist immediately if you develop increasing pain, purulent drainage, severe edema, expanding erythema beyond expected post-peel redness, or fever. These may indicate infection requiring medical intervention unrelated to topical products. For concerns about product tolerance, discontinue use and consult your physician. Normal post-peel experiences include mild stinging upon application, temporary redness increase, and slight warmth. These typically resolve within 10-15 minutes and diminish with continued use.

While The Catalyst alone provides significant TRPV1 antagonism and anti-inflammatory benefits, the four-product protocol addresses different aspects of optimal recovery from chemical peels. The Purifier provides gentle cleansing without barrier disruption, The Catalyst targets inflammation, The Day Formula delivers critical sun protection without irritating chemicals, and The Night Synthesis supports accelerated cellular renewal during peak repair hours.

For budget considerations, prioritize The Catalyst and The Day Formula as the foundational products, adding The Purifier and Night Synthesis as budget allows for comprehensive support.

Chemical peel selection should always be made in consultation with a board-certified dermatologist who can assess your skin type, concerns, and goals. Light peels like glycolic acid peels and salicylic acid peels address mild texture concerns, fine lines, and acne with minimal downtime. Medium-depth treatments like Jessner's peel and TCA peels target more pronounced aging signs, pigmentation, and scarring with moderate recovery periods. Deep phenol peels produce dramatic results for severe photoaging but require extensive downtime and medical supervision. Your dermatologist will recommend the appropriate peel intensity based on your individual factors and desired outcomes.

Yes, the formulations are dermatologist-tested and safe for periorbital application. The eye emulsion referenced in clinical trials used TRPV1-targeting technology, demonstrating significant improvements in fine lines, dark circles, and under-eye texture. Apply products carefully to avoid direct eye contact. If treating the full face including periorbital region after comprehensive chemical peels, use gentle dabbing motions with your ring finger rather than rubbing to avoid mechanical irritation of delicate tissue during the healing phase.

Erythema (redness) duration varies significantly by peel depth and individual healing capacity. Light glycolic acid peels and salicylic acid peels typically produce mild redness lasting 1-3 days. Medium-depth Jessner's peel creates 3-7 days of pronounced erythema, followed by 2-4 weeks of subtle pink tone. TCA peels generate 5-10 days of intense redness with 3-6 weeks of residual color depending on concentration. Deep phenol peels produce weeks of intense erythema with months-long pink tone requiring camouflage. Clinical data demonstrates that TRPV1 antagonism reduces erythema intensity by 21% and may shorten visible redness duration by modulating the inflammatory cascade at its cellular origin. Persistent redness beyond expected timeframes warrants dermatologist evaluation to exclude complications or adverse healing responses.

Physical activity restrictions depend on peel intensity and sweat's impact on compromised skin barriers. After light glycolic acid peels or salicylic acid peels, limit intense exercise for 24-48 hours but gentle walking remains acceptable. For medium-depth Jessner's peel or TCA peels, avoid exercise for 5-7 days as elevated heart rate increases facial blood flow and edema, while sweat introduces bacteria and irritants to healing skin. Deep phenol peels require extended activity restriction per physician guidance. Once you resume exercise, cleanse immediately post-workout using lukewarm water and The Purifier, then reapply The Catalyst and barrier protection. Elevated core temperature can trigger TRPV1 activation, potentially increasing inflammation during the critical healing window. Your dermatologist may adjust these guidelines based on your healing progress and baseline fitness level.

Peeling represents normal and expected epithelial turnover following chemical exfoliation. Resist the urge to pick, pull, or manually remove loosening skin. Forced removal creates irregular texture, prolongs healing, and increases infection and scarring risk. For light glycolic acid peels and salicylic acid peels, gentle flaking typically begins days 2-3 and continues through day 5-7. Jessner's peel and TCA peels produce more dramatic peeling starting days 3-5 and continuing through days 7-14 depending on depth. Apply The Catalyst followed by The Day Formula or Night Synthesis to softened, dampened skin, gently patting rather than rubbing. The peptide complex supports maintaining barrier integrity beneath peeling layers. If peeling occurs in thick sheets with unusual color, or if you notice malodor or yellow-green drainage, contact your dermatologist immediately as these may indicate infection requiring intervention.

Cleansing protocols differ by peel depth. After light glycolic acid peels or salicylic acid peels, resume gentle cleansing after 12-24 hours using lukewarm water and The Purifier. Following medium-depth Jessner's peel or TCA peels, your provider may recommend waiting 24-48 hours before first cleansing, then transitioning to gentle twice-daily cleansing once initial re-epithelialization occurs. Deep phenol peels require physician-supervised cleansing protocols. Regardless of peel type, avoid hot water (activates TRPV1 receptors, increasing inflammation), mechanical cleansing devices, washcloths, or scrubbing motions for minimum 2-3 weeks. Pat skin dry rather than rubbing. Apply The Catalyst to slightly damp skin for enhanced absorption and barrier support during this vulnerable phase.

Tightness, discomfort, and burning sensations represent common post-peel experiences resulting from barrier disruption, inflammation, and altered nerve signaling. Light peels create mild tightness lasting 1-3 days. Medium-depth Jessner's peel and TCA peels generate significant tightness persisting 1-2 weeks as new epithelium forms. Deep phenol peels produce intense discomfort requiring medical management. The TRPV1 receptor mediates these sensory experiences; published research demonstrates that TRPV1 antagonists reduce subjective discomfort scores in post-procedure patients. Apply The Catalyst liberally during this phase, as the biomimetic peptide specifically addresses the receptor pathway transmitting uncomfortable sensations following glycolic acid peels, TCA peels, and other treatments. However, progressively worsening pain, burning that interferes with sleep, or discomfort accompanied by unusual drainage requires immediate physician evaluation to exclude complications.

Cold therapy provides benefits for post-peel inflammation management when applied correctly. During the first 48 hours after any chemical peel, gentle cooling reduces edema and provides comfort. Use clean, soft cloths dampened with cool (not ice-cold) water, applied for 10-15 minutes every 2-3 hours. Avoid direct ice application as extreme cold can damage healing tissue and paradoxically trigger inflammatory responses. Never apply ice or cold compresses over topical products; instead, cool first, pat dry gently, then apply The Catalyst. Cold temperatures may enhance TRPV1-targeting peptide effectiveness by reducing baseline receptor activity following glycolic acid peels, salicylic acid peels, Jessner's peel, TCA peels, and other treatments. Discontinue cold therapy if you experience increased pain, numbness, or blanching that persists beyond compress removal.

While both are light chemical peels, glycolic acid peels and salicylic acid peels produce slightly different recovery experiences. Glycolic acid peels penetrate more broadly across skin layers, creating general exfoliation with mild flaking and 1-3 days of pinkness. Salicylic acid peels target oil-rich areas more selectively, making them particularly effective for acne-prone skin, with recovery typically involving 2-4 days of localized flaking around pores and minimal redness. Both benefit from immediate post-treatment TRPV1 antagonism with The Catalyst to minimize inflammatory responses. Recovery protocols remain similar regardless of peel type, though salicylic acid peels may require special attention to avoid over-drying in treated areas.What's the difference between Jessner's peel and TCA peels?Jessner's peel combines resorcinol, salicylic acid, and lactic acid for controlled medium-depth exfoliation, producing 5-7 days of peeling with moderate downtime. TCA (trichloroacetic acid) peels achieve variable depths depending on concentration, light TCA (10-20%) creates superficial exfoliation similar to stronger glycolic acid peels, while medium TCA (25-35%) penetrates deeper than Jessner's peel with 7-10 days of pronounced peeling. Higher concentration TCA approaches deep peel territory with extended recovery. Both Jessner's peel and medium-depth TCA peels benefit significantly from TRPV1-targeting post-care protocols to manage inflammatory responses and support optimal collagen remodeling during the critical 4-6 week healing window.

While no specific dietary restrictions apply to most chemical peel recoveries, certain considerations optimize healing. Avoid alcohol for 48-72 hours after any peel, as it dilates blood vessels and may increase swelling and redness. For medium-depth Jessner's peel or TCA peels, some dermatologists recommend avoiding blood-thinning supplements like fish oil, vitamin E, or NSAIDs for several days post-treatment to minimize bruising risk. Spicy foods may trigger facial flushing through TRPV1 activation, potentially increasing discomfort after glycolic acid peels or other treatments. Focus on hydration and anti-inflammatory foods rich in omega-3 fatty acids, antioxidants, and vitamin C to support healing. Consult your dermatologist about specific dietary recommendations based on your peel type and medical history.