Dr. Rossi Derm MD The Catalyst age-defying serum in black bottle on white background
closeup of two droplets of translucent skincare serum on white background
Dr. Rossi Derm MD The Catalyst age-defying serum in black bottle, travel size
Two side-by-side images of a woman's cheek from The Catalyst clinical trials. Image on the left displays woman's cheek before using The Catalyst, and the image on the right showsher cheek after using The Catalyst for four weeks.
Two images of a woman's brow from The Catalyst clinical trials. Image on the top displays woman's brow before using The Catalyst, and the image on the bottom shows her brow after using The Catalyst for four weeks.
Bio-Theriac Complex: fights signs of aging and sensitivity. Saccharide blend: boosts hydration. Tamarindus Indica seed gum: helps promote smoother skin.
Dr. Rossi Derm MD The Catalyst age-defying serum in black bottle on white background
closeup of two droplets of translucent skincare serum on white background
Dr. Rossi Derm MD The Catalyst age-defying serum in black bottle, travel size
Two side-by-side images of a woman's cheek from The Catalyst clinical trials. Image on the left displays woman's cheek before using The Catalyst, and the image on the right showsher cheek after using The Catalyst for four weeks.
Two images of a woman's brow from The Catalyst clinical trials. Image on the top displays woman's brow before using The Catalyst, and the image on the bottom shows her brow after using The Catalyst for four weeks.
Bio-Theriac Complex: fights signs of aging and sensitivity. Saccharide blend: boosts hydration. Tamarindus Indica seed gum: helps promote smoother skin.
Rated 4.7 out of 5
Based on 63 reviews

The Catalyst

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Intense Renewing Serum

Size 30 mL
+
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SUSTAINABLE BEAUTY

ALWAYS TESTED ON SENSITIVE SKIN

PARABEN, FRAGRANCE, AND DYE-FREE

DERMATOLOGIST APPROVED

CERTIFIED CRUELTY FREE

Approved and recognized by The North American Contact Dermatitis Society

This transformative silky daily serum, packed with Bio-Theriac® complex, is clinically proven to help even tone while delivering visibly smoother skin. While combatting skin sensitivity, this serum significantly boosts skin firmness and measurably diminishes the appearance of fine lines and wrinkles.

What sets this serum apart is its unique ability to address multiple skin concerns in one powerful formula. The innovative blend of active ingredients works harmoniously for a youthful and rejuvenated complexion.

The Catalyst Intense Renewing Serum by Dr. Rossi DERM MD is appropriate for all skin types, including sensitive, dry, combination, and oily skin.

Key Ingredients

Bio-Theriac® complex

Dr. Rossi’s proprietary ingredient composite harnesses the power of biomimetic sea anemone peptide, niacinamide, and hyaluronic acid in a unique, optimized ratio to help fight the visible signs of premature aging caused by sensitization in skin.

Saccharide Blend 

This specially curated blend of saccharides, or sugars, works in tandem with hyaluronic acid to help lock moisture into the skin, boosting and maintaining hydration.  

Tamarindus Indica Seed Gum

Extracted from tamarind seeds, this potent plant derivative has been shown to help promote smoother skin and, with its well documented antioxidant properties, help prevent visible signs of premature aging.

Bio-Theriac® complex

Dr. Rossi’s proprietary ingredient composite harnesses the power of biomimetic sea anemone peptide, niacinamide, and hyaluronic acid in a unique, optimized ratio to help fight the visible signs of premature aging caused by sensitization in skin.

Saccharide Blend 

This specially curated blend of saccharides, or sugars, works in tandem with hyaluronic acid to help lock moisture into the skin, boosting and maintaining hydration.  

Tamarindus Indica Seed Gum

Extracted from tamarind seeds, this potent plant derivative has been shown to help promote smoother skin and, with its well documented antioxidant properties, help prevent visible signs of premature aging.

All Ingredients:  Aqua/Water/Eau, Butylene Glycol, Sea Water (Maris Aqua), Glycerin, Niacinamide, Xylitylglucoside, Anhydroxylitol, Maltodextrin, Hydroxyethylcellulose, Propanediol, Caprylyl Glycol, 1,2-Hexanediol, Xanthan Gum, Hydroxyacetophenone, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Xylitol, Tamarindus Indica Seed Gum, Hydrogenated Lecithin, Sodium Phytate, Nasturtium Officinale Flower/Leaf/Stem Extract, Phenethyl Alcohol, Equisetum Arvense Extract, Urtica Dioica (Nettle) Extract, Porphyridium Cruentum Extract, Disodium Phosphate, Sodium Phosphate, Sodium Hyaluronate, Citric Acid, Pentapeptide-59, Phenoxyethanol, Polysorbate 60, Ethylhexylglycerin, Sodium Chloride

Gently massage onto face and neck. Use daily AM & PM.

Goes well with

 

As seen in

CLINICAL TRIAL RESULTS

AFTER 4 WEEKS
BEFORE
AFTER 4 WEEKS
  • 87% Agree Skin Looks Rejuvenated*
  • 67% Smoother Skin*
  • Up to 100% Reduction in Redness*
  • Up to 57% More Elastic Skin*

*In a clinical study on 31 men and women

WHY DR. ROSSI?

SENSITIVE SKIN, SPECIAL CARE

Dr. Rossi embarked on a mission to rethink skin care and create de-aging solutions appropriate for all, regardless of age, gender, or level of skin sensitivity. His goal: To combat the signs of skin aging while suppressing sensitization.

After treating both those patients battling cancer and those seeking cosmetic treatments, Dr. Rossi noticed that when his patients looked better, they felt better and healed more quickly. But his patients with sensitive skin couldn’t get the results they wanted because products in the market aggravated their sensitivity.

THE BREAKTHROUGH

Dr. Rossi developed his landmark formulas with his proprietary Bio-Theriac® complex, which helps correct the visible effects of aging and environmental aggressors while reducing sensitization. Dr. Rossi’s formulas exclude the use of ingredients that neither support skin health nor aid in its appearance, such as irritants, fillers, and fragrance.

The result is a relentlessly perfected and tested, revolutionary line of luxury treatments that will reveal your healthiest looking, most vibrant skin regardless of your gender identity, complexion, or skin condition. 

NEXT-GENERATION MEDICAL-GRADE SKIN CARE

"Skin sensitivity is not just discomfort—it can be tied to one of the root causes of premature skin aging. What we put on our skin matters, so if a product causes irritation it’s a big red flag and you’re probably doing more harm than good to your skin. I created this line of clean, high-performing products to restore skin to its youthful, healthy look while remaining non-irritating and safe to use on all skin types, including on the skin conditions of my cancer patients. This type of medical-grade skin care has never been done before."

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FAQ – The Catalyst

This powerful formula is specifically designed to rejuvenate and revitalize the skin, targeting key concerns such as fine lines, wrinkles, uneven tone, and texture. The advanced blend of active ingredients works together to promote cell turnover, boost collagen production, and improve overall skin health. The Catalyst Dr. Rossi Derm MD Intense Renewing Serum helps fight the visible signs of premature aging caused by sensitization in the skin, diminishing the appearance of wrinkles and boosting elasticity. Serums are highly concentrated with active ingredients yet lightweight and have a wonderful glass finish.

These serums are typically lightweight and fast-absorbing, making them suitable for all skin types, including oily skin. In fact, using a renewing serum can help balance the skin's oil production and improve overall skin health. The Catalyst has been formulated to suit all skin types, including oily and sensitive skin.

Consistency is key when it comes to skincare products, as the active ingredients need time to work their magic and deliver the desired benefits. The Catalyst is a daily serum that can be used in the morning and at night. To get the most out of your serum, start by cleansing your skin thoroughly to remove any excess oil and dirt, then apply a thin layer of the serum to your face and neck, avoiding the eye area. Follow up with a lightweight moisturizer to lock in the serum and provide hydration.

average rating 4.7 out of 5
Based on 63 reviews
  • 5 Stars
    44 Reviews
  • 4 Stars
    18 Reviews
  • 3 Stars
    1 Review
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98% of reviewers would recommend this product to a friend
Customer photos and videos
63 Reviews
Reviewed by Dana M., from United States
Verified Buyer
I recommend this product
Skin Type
Sensitive
Age Range
25 - 34
Rated 5 out of 5
Review posted

My favorite product of all time

Not just a hydrator- glass skin always

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Reviewed by Cesar Della B., from United States
Verified Buyer
I recommend this product
Age Range
45 - 54
Rated 5 out of 5
Review posted

Outstanding product!

The catalyst is an excellent and high quality face cream.

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Reviewed by Dawn G., from United States
Verified Buyer
I recommend this product
Skin Type
Combination
Age Range
35 - 44
Rated 5 out of 5
Review posted

Soft , supple, hydrated glow

My title says it all, but your skin will love you after using this. My skin looked dewy and glowy all day without being oily or shiny. Texture wise, the skin feels hydrated and I’d be struggling with peeling and dry patches for weeks and with just one use they were gone! Amazing product

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Reviewed by Alessandra A., from United States
Verified Buyer
I recommend this product
Skin Type
Combination
Age Range
35 - 44
Rated 5 out of 5
Review posted

Finally found my everyday youth secret ☺️

I have a combination skin, very difficult to manage.. all the products I used for years where always too heavy on my skin and at the same time left me with some dry spots. I’m so glad Dr. Rossi created this line, this serum is phenomenal.. you don’t need too much, but your skin feels hydrated and balanced afterwards and stays for all day. Thanks to his expertise and research I could not be more very pleased with his products.

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Reviewed by Daniele M., from United States
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

❤️

Amazing product

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